The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

BACKGROUND: Reproducibility is a fundamental requirement in scientific experiments. Some recent publications have claimed that microarrays are unreliable because lists of differentially expressed genes (DEGs) are not reproducible in similar experiments. Meanwhile, new statistical methods for identif...

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Main Authors: Shi, Leming, Jones, Wendell D, Jensen, Roderick V, Harris, Stephen C, Perkins, Roger G, Goodsaid, Federico M, Guo, Lei, Croner, Lisa J, Boysen, Cecilie, Fang, Hong, Qian, Feng, Amur, Shashi, Bao, Wenjun, Barbacioru, Catalin C, Bertholet, Vincent, Cao, Xiaoxi Megan, Chu, Tzu-Ming, Collins, Patrick J, Fan, Xiao-hui, Frueh, Felix W, Fuscoe, James C, Guo, Xu, Han, Jing, Herman, Damir, Hong, Huixiao, Kawasaki, Ernest S, Li, Quan-Zhen, Luo, Yuling, Ma, Yunqing, Mei, Nan, Peterson, Ron L, Puri, Raj K, Shippy, Richard, Su, Zhenqiang, Sun, Yongming Andrew, Sun, Hongmei, Thorn, Brett, Turpaz, Yaron, Wang, Charles, Wang, Sue Jane, Warrington, Janet A, Willey, James C, Wu, Jie, Xie, Qian, Zhang, Liang, Zhang, Lu, Zhong, Sheng, Wolfinger, Russell D, Tong, Weida
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2008
Ábhair:
Proceedings
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2537561/
https://ncbi.nlm.nih.gov/pubmed/18793455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-S9-S10
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