The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

BACKGROUND: Reproducibility is a fundamental requirement in scientific experiments. Some recent publications have claimed that microarrays are unreliable because lists of differentially expressed genes (DEGs) are not reproducible in similar experiments. Meanwhile, new statistical methods for identif...

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Detalhes bibliográficos
Main Authors: Shi, Leming, Jones, Wendell D, Jensen, Roderick V, Harris, Stephen C, Perkins, Roger G, Goodsaid, Federico M, Guo, Lei, Croner, Lisa J, Boysen, Cecilie, Fang, Hong, Qian, Feng, Amur, Shashi, Bao, Wenjun, Barbacioru, Catalin C, Bertholet, Vincent, Cao, Xiaoxi Megan, Chu, Tzu-Ming, Collins, Patrick J, Fan, Xiao-hui, Frueh, Felix W, Fuscoe, James C, Guo, Xu, Han, Jing, Herman, Damir, Hong, Huixiao, Kawasaki, Ernest S, Li, Quan-Zhen, Luo, Yuling, Ma, Yunqing, Mei, Nan, Peterson, Ron L, Puri, Raj K, Shippy, Richard, Su, Zhenqiang, Sun, Yongming Andrew, Sun, Hongmei, Thorn, Brett, Turpaz, Yaron, Wang, Charles, Wang, Sue Jane, Warrington, Janet A, Willey, James C, Wu, Jie, Xie, Qian, Zhang, Liang, Zhang, Lu, Zhong, Sheng, Wolfinger, Russell D, Tong, Weida
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Proceedings
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2537561/
https://ncbi.nlm.nih.gov/pubmed/18793455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-S9-S10
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