The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

BACKGROUND: Reproducibility is a fundamental requirement in scientific experiments. Some recent publications have claimed that microarrays are unreliable because lists of differentially expressed genes (DEGs) are not reproducible in similar experiments. Meanwhile, new statistical methods for identif...

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Bibliografiske detaljer
Main Authors: Shi, Leming, Jones, Wendell D, Jensen, Roderick V, Harris, Stephen C, Perkins, Roger G, Goodsaid, Federico M, Guo, Lei, Croner, Lisa J, Boysen, Cecilie, Fang, Hong, Qian, Feng, Amur, Shashi, Bao, Wenjun, Barbacioru, Catalin C, Bertholet, Vincent, Cao, Xiaoxi Megan, Chu, Tzu-Ming, Collins, Patrick J, Fan, Xiao-hui, Frueh, Felix W, Fuscoe, James C, Guo, Xu, Han, Jing, Herman, Damir, Hong, Huixiao, Kawasaki, Ernest S, Li, Quan-Zhen, Luo, Yuling, Ma, Yunqing, Mei, Nan, Peterson, Ron L, Puri, Raj K, Shippy, Richard, Su, Zhenqiang, Sun, Yongming Andrew, Sun, Hongmei, Thorn, Brett, Turpaz, Yaron, Wang, Charles, Wang, Sue Jane, Warrington, Janet A, Willey, James C, Wu, Jie, Xie, Qian, Zhang, Liang, Zhang, Lu, Zhong, Sheng, Wolfinger, Russell D, Tong, Weida
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Proceedings
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2537561/
https://ncbi.nlm.nih.gov/pubmed/18793455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-S9-S10
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