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Intracellular pH regulates superoxide production by the macula densa

We hypothesized that elevated macula densa intracellular pH (pH(i)) during tubuloglomerular feedback enhances O(2)(−) production from NAD(P)H oxidase. Microdissected thick ascending limbs from rabbits with intact macula densa were cannulated and perfused with physiological saline. When luminal NaCl...

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Detalhes bibliográficos
Main Authors: Liu, Ruisheng, Carretero, Oscar A., Ren, Yilin, Wang, Hong, Garvin, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536876/
https://ncbi.nlm.nih.gov/pubmed/18667487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90204.2008
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