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Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling
Although production of reactive oxygen species (ROS) such as superoxide (O(2)(·−)) has been implicated in chronic hypoxia-induced pulmonary hypertension (PH) and pulmonary vascular remodeling, the transcription factors and gene targets through which ROS exert their effects have not been completely i...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536799/ https://ncbi.nlm.nih.gov/pubmed/18599502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90293.2008 |
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