Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis

One prime feature of alcoholic liver disease (ALD) is iron accumulation in hepatic macrophages/Kupffer cells (KC) associated with enhanced NF-κB activation. Our recent work demonstrates a peroxynitrite-mediated transient rise in intracellular labile iron (ILI) as novel signaling for endotoxin-induce...

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Detalhes bibliográficos
Main Authors: Xiong, Shigang, She, Hongyun, Zhang, An-Sheng, Wang, Jiaohong, Mkrtchyan, Hasmik, Dynnyk, Alla, Gordeuk, Victor R., French, Samuel W., Enns, Caroline A., Tsukamoto, Hidekazu
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536779/
https://ncbi.nlm.nih.gov/pubmed/18599584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90327.2008
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