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Functions of Acidic Transmembrane Residues in Human Melanocortin-3 Receptor Binding and Activation
The melanocortin-3 receptor (MC3R) is an important regulator of energy homeostasis, inflammation, and cardiovascular function. Inactivating mutations in MC3R gene are associated with childhood obesity. How MC3R binds to its ligands has rarely been studied. In the present study, we systematically mut...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536753/ https://ncbi.nlm.nih.gov/pubmed/18614155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.05.026 |
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