Amplification of pulsatile glucagon counterregulation by switch-off of α-cell-suppressing signals in streptozotocin-treated rats

Glucagon counterregulation (GCR) is a key protection against hypoglycemia that is compromised in diabetes via an unknown mechanism. To test the hypothesis that α-cell-inhibiting signals that are switched off during hypoglycemia amplify GCR, we studied streptozotocin (STZ)-treated male Wistar rats an...

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Hlavní autoři: Farhy, Leon S., Du, Zhongmin, Zeng, Qiang, Veldhuis, Paula P., Johnson, Michael L., Brayman, Kenneth L., McCall, Anthony L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536740/
https://ncbi.nlm.nih.gov/pubmed/18577688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90372.2008
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