Association of Basal Hyperglucagonemia with Impaired Glucagon Counterregulation in Type 1 Diabetes

Glucagon counterregulation (GCR) protects against hypoglycemia, but is impaired in type 1 diabetes (T1DM). A model-based analysis of in vivo animal data predicts that the GCR defects are linked to basal hyperglucagonemia. To test this hypothesis we studied the relationship between basal glucagon (Ba...

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Detalhes bibliográficos
Main Authors: Farhy, Leon S., Chan, Alice, Breton, Marc D., Anderson, Stacey M., Kovatchev, Boris P., McCall, Anthony L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288769/
https://ncbi.nlm.nih.gov/pubmed/22403550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00040
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