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Toward the Total Synthesis of FR901483: Concise Synthesis of the Azatricyclic Skeleton
A concise synthesis of the azatricyclic core of FR901483 has been accomplished using a novel strategy that involves a nucleophilic addition to an N-acyl iminium ion, a ring closing metathesis, a diastereoselective hydroboration and a lactone-lactam rearrangement that worked well in a preliminary mod...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536713/ https://ncbi.nlm.nih.gov/pubmed/17555359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo070732a |
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