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Bisphosphine-Catalyzed Mixed Double-Michael Reactions: Asymmetric Synthesis of Oxazolidines, Thiazolidines, and Pyrrolidines

Bisphosphine-catalyzed mixed double-Michael reactions have been developed to afford β-amino carbonyl derivatives of oxazolidines, thiozolidines, and pyrrolidines in excellent yields and with high diastereoselectivities. Efficient reactions between amino acid-derived pronucleophiles, e.g., β-amino al...

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Bibliographic Details
Main Authors: Sriramurthy, Vardhineedi, Barcan, Gregg A., Kwon, Ohyun
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536693/
https://ncbi.nlm.nih.gov/pubmed/17924625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja073754n
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