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Low-dose methotrexate reduces peripheral nerve injury-evoked spinal microglial activation and neuropathic pain behavior in rats

Peripheral nerve injuries that provoke neuropathic pain are associated with microglial activation in the spinal cord. We have investigated the characteristics of spinal microglial activation in three distinct models of peripheral neuropathic pain: spared nerve injury (SNI), chronic constriction inju...

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Detalhes bibliográficos
Main Authors: Scholz, Joachim, Abele, Andrea, Marian, Claudiu, Häussler, Annett, Herbert, Teri A., Woolf, Clifford J., Tegeder, Irmgard
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536692/
https://ncbi.nlm.nih.gov/pubmed/18215468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2007.11.019
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