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Low-dose methotrexate reduces peripheral nerve injury-evoked spinal microglial activation and neuropathic pain behavior in rats

Peripheral nerve injuries that provoke neuropathic pain are associated with microglial activation in the spinal cord. We have investigated the characteristics of spinal microglial activation in three distinct models of peripheral neuropathic pain: spared nerve injury (SNI), chronic constriction inju...

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Autors principals: Scholz, Joachim, Abele, Andrea, Marian, Claudiu, Häussler, Annett, Herbert, Teri A., Woolf, Clifford J., Tegeder, Irmgard
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536692/
https://ncbi.nlm.nih.gov/pubmed/18215468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2007.11.019
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