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Structure-Activity Relationship Studies of Gonadotropin Releasing Hormone Antagonists Containing S-aryl/alkyl Norcysteines and their Oxidized Derivatives
A series of acyline analogues incorporating l- and d- isomers of S-arylated/alkylated norcysteines [Ncy(R), where R is 2-naphthyl, methyl and isopropyl] at positions 1, 4, 7 and 10 were synthesized. Some of these analogues were mono- and di-oxidized to sulfoxides and sulfones. All of the analogues o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536683/ https://ncbi.nlm.nih.gov/pubmed/17402723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0613931 |
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