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Endocytic Delivery of Vancomycin Mediated by a Synthetic Cell Surface Receptor: Rescue of Bacterially-Infected Mammalian Cells and Tissue Targeting In Vivo

Extracellular domains of internalizing cell surface receptors are often targeted to enable drug delivery through the mechanism of receptor-mediated endocytosis. To circumvent natural receptors required for endocytic drug delivery, we constructed a small artificial cell surface receptor comprising th...

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Main Authors: Boonyarattanakalin, Siwarutt, Hu, Jianfang, Dykstra-Rummel, Sheryl A., August, Avery, Peterson, Blake R.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536652/
https://ncbi.nlm.nih.gov/pubmed/17212394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja067674f
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