A Synthetic Mimic of Human Fc Receptors: Defined Chemical Modification of Cell Surfaces Enables Efficient Endocytic Uptake of Human Immunoglobulin-G

Binding of ligands to macromolecular receptors on the surface of mammalian cells often results in ligand uptake through receptor-mediated endocytosis. Certain human leukocytes and epithelial cells express Fc receptors (FcRs) that bind and internalize antibodies through this mechanism. To mimic this...

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Hlavní autoři: Boonyarattanakalin, Siwarutt, Martin, Scott E., Sun, Qi, Peterson, Blake R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528877/
https://ncbi.nlm.nih.gov/pubmed/16939269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja062377w
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