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Bilayer mechanical properties regulate transmembrane helix mobility and enzymatic state of CD39
CD39 can exist in at least two distinct functional states depending on the presence and intact membrane integration of its two transmembrane helices. In native membranes, the transmembrane helices undergo dynamic rotational motions that are required for enzymatic activity and are regulated by substr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536646/ https://ncbi.nlm.nih.gov/pubmed/17198399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061052p |
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