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Fluid flow induces mechanosensitive ATP release, calcium signalling and Cl(−) transport in biliary epithelial cells through a PKCζ-dependent pathway
ATP in bile is a potent secretogogue, stimulating cholangiocyte Cl(−) and fluid secretion via binding to membrane P2 receptors, though the physiological stimuli involved in biliary ATP release are unknown. The goal of the present studies was to determine the potential role of fluid flow in biliary A...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536582/ https://ncbi.nlm.nih.gov/pubmed/18388137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.153015 |
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