Fluid flow induces mechanosensitive ATP release, calcium signalling and Cl(−) transport in biliary epithelial cells through a PKCζ-dependent pathway

ATP in bile is a potent secretogogue, stimulating cholangiocyte Cl(−) and fluid secretion via binding to membrane P2 receptors, though the physiological stimuli involved in biliary ATP release are unknown. The goal of the present studies was to determine the potential role of fluid flow in biliary A...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Woo, Kangmee, Dutta, Amal K, Patel, Vishal, Kresge, Charles, Feranchak, Andrew P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2008
Konular:
Alimentary
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536582/
https://ncbi.nlm.nih.gov/pubmed/18388137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.153015
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