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Regulation of Purinergic Signaling in Biliary Epithelial Cells by Exocytosis of SLC17A9-dependent ATP-enriched Vesicles

ATP in bile is a potent secretogogue, stimulating biliary epithelial cell (BEC) secretion through binding apical purinergic receptors. In response to mechanosensitive stimuli, BECs release ATP into bile, although the cellular basis of ATP release is unknown. The aims of this study in human and mouse...

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Detalhes bibliográficos
Main Authors: Sathe, Meghana N., Woo, Kangmee, Kresge, Charles, Bugde, Abhijit, Luby-Phelps, Kate, Lewis, Matthew A., Feranchak, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137107/
https://ncbi.nlm.nih.gov/pubmed/21613220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.232868
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