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Identification of Osteopontin as a Novel Ligand for the Integrin α8β1 and Potential Roles for This Integrin–Ligand Interaction in Kidney Morphogenesis

Epithelio–mesenchymal interactions during kidney organogenesis are disrupted in integrin α8β1-deficient mice. However, the known ligands for integrin α8β1—fibronectin, vitronectin, and tenascin-C—are not appropriately localized to mediate all α8β1 functions in the kidney. Using a method of general u...

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Detalles Bibliográficos
Main Authors: Denda, Sumiko, Reichardt, Louis F., Müller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC25364/
https://ncbi.nlm.nih.gov/pubmed/9614184
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