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Total Synthesis of (±)-Phomactin B2 via an Intramolecular Cyclohexadienone Annulation of a Chromium Carbene Complex

A total synthesis of (±)-phomactin B2 is described which has as its key step the intramolecular cyclohexadienone annulation of a Fischer carbene complex. The requisite carbene complex was prepared from geraniol in 11 steps and 12 % overall yield. The key cyclohexadienone annulation produced both rin...

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Bibliografiske detaljer
Main Authors: Huang, Jie, Wu, Chunrui, Wulff, William D.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535905/
https://ncbi.nlm.nih.gov/pubmed/17929921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja074275r
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