Rapid “open-source” engineering of customized zinc-finger nucleases for highly efficient gene modification

SUMMARY: Custom-made zinc-finger nucleases (ZFNs) can induce targeted genome modifications with high efficiency in cell types including Drosophila, C. elegans, plants, and humans. A bottleneck in the application of ZFN technology has been the generation of highly specific engineered zinc-finger arra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Maeder, Morgan L., Thibodeau-Beganny, Stacey, Osiak, Anna, Wright, David A., Anthony, Reshma M., Eichtinger, Magdalena, Jiang, Tao, Foley, Jonathan E., Winfrey, Ronnie J., Townsend, Jeffrey A., Unger-Wallace, Erica, Sander, Jeffry D., Müller-Lerch, Felix, Fu, Fengli, Pearlberg, Joseph, Göbel, Carl, Dassie, Justin P., Pruett-Miller, Shondra M., Porteus, Matthew H., Sgroi, Dennis C., Iafrate, A. John, Dobbs, Drena, McCray, Paul B., Cathomen, Toni, Voytas, Daniel F., Joung, J. Keith
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535758/
https://ncbi.nlm.nih.gov/pubmed/18657511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.06.016
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg