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The Rate and Character of Spontaneous Mutation in Thermus thermophilus
Selection of spontaneous, loss-of-function mutations at two chromosomal loci (pyrF and pyrE) enabled the first molecular-level analysis of replication fidelity in the extremely thermophilic bacterium Thermus thermophilus. Two different methods yielded similar mutation rates, and mutational spectra d...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2535672/ https://ncbi.nlm.nih.gov/pubmed/18723895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.089086 |
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