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The Rate and Character of Spontaneous Mutation in Thermus thermophilus

Selection of spontaneous, loss-of-function mutations at two chromosomal loci (pyrF and pyrE) enabled the first molecular-level analysis of replication fidelity in the extremely thermophilic bacterium Thermus thermophilus. Two different methods yielded similar mutation rates, and mutational spectra d...

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Bibliografski detalji
Glavni autori: Mackwan, Reena R., Carver, Geraldine T., Kissling, Grace E., Drake, John W., Grogan, Dennis W.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535672/
https://ncbi.nlm.nih.gov/pubmed/18723895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.089086
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