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An Unusual Pattern of Spontaneous Mutations Recovered in the Halophilic Archaeon Haloferax volcanii

Spontaneous mutations in the orotate:phosphoribosyl transferase (pyrE2) gene of the halophilic archaeon Haloferax volcanii were selected by 5-fluoroorotic acid plus uracil at a rate of ∼2 × 10(−8)/cell division in fluctuation and null-fraction tests but ∼6 × 10(−8)/cell division in mutation-accumula...

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Detalhes bibliográficos
Main Authors: Mackwan, Reena R., Carver, Geraldine T., Drake, John W., Grogan, Dennis W.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2007 by the Genetics Society of America 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1893060/
https://ncbi.nlm.nih.gov/pubmed/17194771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.069666
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