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Fluoride Induces Endoplasmic Reticulum Stress and Inhibits Protein Synthesis and Secretion
BACKGROUND: Exposure to excessive amounts of fluoride (F(−)) causes dental fluorosis in susceptible individuals; however, the mechanism of F(−)-induced toxicity is unclear. Previously, we have shown that high-dose F(−) activates the unfolded protein response (UPR) in ameloblasts that are responsible...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Institute of Environmental Health Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2535613/ https://ncbi.nlm.nih.gov/pubmed/18795154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.11375 |
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