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Structure of the DNA-binding domain of the response regulator PhoP from Mycobacterium tuberculosis

The PhoP-PhoR two-component signaling system from Mycobacterium tuberculosis is essential for the virulence of the tubercle bacillus. The response regulator, PhoP, regulates expression of over 110 genes. In order to elucidate the regulatory mechanism of PhoP, we determined the crystal structure of i...

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Bibliografski detalji
Glavni autori: Wang, Shuishu, Engohang-Ndong, Jean, Smith, Issar
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535579/
https://ncbi.nlm.nih.gov/pubmed/18052041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700970a
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