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Structure of the DNA-binding domain of the response regulator PhoP from Mycobacterium tuberculosis
The PhoP-PhoR two-component signaling system from Mycobacterium tuberculosis is essential for the virulence of the tubercle bacillus. The response regulator, PhoP, regulates expression of over 110 genes. In order to elucidate the regulatory mechanism of PhoP, we determined the crystal structure of i...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2535579/ https://ncbi.nlm.nih.gov/pubmed/18052041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700970a |
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