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Inhibition of human immunodeficiency virus by using an oligonucleoside methylphosphonate targeted to the tat-3 gene.

Antiviral effects were characterized for two oligodeoxyribonucleoside methylphosphonates synthesized in an antisense (3'-TCTTAACC-5') or a sense (5'-AGAATTGG-3') orientation, based on the RNA sequence of the first splice acceptor site of the tat-3 gene of human immunodeficiency v...

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Bibliographic Details
Main Authors: Zaia, J A, Rossi, J J, Murakawa, G J, Spallone, P A, Stephens, D A, Kaplan, B E, Eritja, R, Wallace, R B, Cantin, E M
Format: Artigo
Language:Inglês
Published: 1988
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC253546/
https://ncbi.nlm.nih.gov/pubmed/2458490
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