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Inhibition of human immunodeficiency virus by using an oligonucleoside methylphosphonate targeted to the tat-3 gene.

Antiviral effects were characterized for two oligodeoxyribonucleoside methylphosphonates synthesized in an antisense (3'-TCTTAACC-5') or a sense (5'-AGAATTGG-3') orientation, based on the RNA sequence of the first splice acceptor site of the tat-3 gene of human immunodeficiency virus (HIV) (5'...AGA...

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Sparad:
I publikationen:J Virol
Huvudupphov: Zaia, J A, Rossi, J J, Murakawa, G J, Spallone, P A, Stephens, D A, Kaplan, B E, Eritja, R, Wallace, R B, Cantin, E M
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1988
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2458490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.10.3914-3917.1988
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