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THE ROLE OF ASPARTATE 143 IN E. coli tRNA-GUANINE TRANSGLYCOSYLASE: ALTERATION OF HETEROCYCLIC SUBSTRATE SPECIFICITY

tRNA-guanine transglycosylase (TGT) is a key enzyme involved in the post-transcriptional modification of certain tRNAs in their anticodon wobble positions with queuine. In order to maintain the correct Watson-Crick base pairing properties of the wobble base (and hence proper translation of the genet...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Todorov, Katherine Abold, Garcia, George A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533737/
https://ncbi.nlm.nih.gov/pubmed/16401090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051863d
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