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AMPK Represses TOP mRNA Translation But Not Global Protein Synthesis in Liver

The AMP-activated protein kinase (AMPK) represses signaling through the mammalian target of rapamycin complex 1 (mTORC1). In muscle, repression of mTORC1 leads to a reduction in global protein synthesis. In contrast, repression of mTORC1 in the liver has no immediate effect on global protein synthes...

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Bibliografische gegevens
Hoofdauteurs: Reiter, Ali K., Bolster, Douglas R., Crozier, Stephen J., Kimball, Scot R., Jefferson, Leonard S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533707/
https://ncbi.nlm.nih.gov/pubmed/18638456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.07.025
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