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Activation of the Mammalian Target of Rapamycin Complex 1 is Both Necessary and Sufficient to Stimulate Eukaryotic Initiation Factor 2Bε mRNA Translation and Protein Synthesis

In a previous study we demonstrated a requirement for activation of mTORC1 in the stimulation of eIF2Bε mRNA translation in skeletal muscle in response to resistance exercise. Although that study established the necessity of mTORC1 activation, the experimental model used did not lend itself readily...

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Detalhes bibliográficos
Main Authors: Kubica, Neil, Crispino, Jamie L., Gallagher, James W., Kimball, Scot R., Jefferson, Leonard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601645/
https://ncbi.nlm.nih.gov/pubmed/18556237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2008.04.010
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