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Mechanisms of Human Immunodeficiency Virus Type 1 Concerted Integration Related to Strand Transfer Inhibition and Drug Resistance

The “strand transfer inhibitors” of human immunodeficiency virus type-1 (HIV-1) integrase (IN), so named because of their pronounced selectivity for inhibiting strand transfer over 3′ OH processing, block virus replication in vivo and ex vivo and prevent concerted integration in vitro. We explored t...

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Detalhes bibliográficos
Main Authors: Zahm, Jacob A., Bera, Sibes, Pandey, Krishan K., Vora, Ajaykumar, Stillmock, Kara, Hazuda, Daria, Grandgenett, Duane P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533447/
https://ncbi.nlm.nih.gov/pubmed/18591263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00271-08
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