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Wnt, Activin, and BMP Signaling Regulate Distinct Stages in the Developmental Pathway from Embryonic Stem Cells to Blood

The embryonic stem cell differentiation system was used to define the roles of the Activin/Nodal, BMP, and canonical Wnt signaling pathways at three distinct developmental stages during hematopoietic ontogeny: induction of a primitive streak-like population, formation of Flk1(+) mesoderm, and induct...

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Detalhes bibliográficos
Main Authors: Nostro, M. Cristina, Cheng, Xin, Keller, Gordon M., Gadue, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533280/
https://ncbi.nlm.nih.gov/pubmed/18371422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2007.10.011
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