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Antagonism of dopamine D2 receptor/β-arrestin 2 interaction is a common property of clinically effective antipsychotics

Since the unexpected discovery of the antipsychotic activity of chlorpromazine, a variety of therapeutic agents have been developed for the treatment of schizophrenia. Despite differences in their activities at various neurotransmitter systems, all clinically effective antipsychotics share the abili...

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Bibliografiske detaljer
Main Authors: Masri, Bernard, Salahpour, Ali, Didriksen, Michael, Ghisi, Valentina, Beaulieu, Jean-Martin, Gainetdinov, Raul R., Caron, Marc G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533245/
https://ncbi.nlm.nih.gov/pubmed/18768802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803522105
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