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A conserved salt bridge critical for GABA(A) receptor function and loop C dynamics
Chemical signaling in the brain involves rapid opening and closing of ligand gated ion channels (LGICs). LGICs are allosteric membrane proteins that transition between multiple conformational states (closed, open, and desensitized) in response to ligand binding. While structural models of cys-loop L...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533236/ https://ncbi.nlm.nih.gov/pubmed/18757734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801854105 |
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