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RCS1, a substrate of APC/C, controls the metaphase to anaphase transition
The anaphase-promoting complex/cyclosome (APC/C) controls the onset of anaphase by targeting securin for destruction. We report here the identification and characterization of a substrate of APC/C, RCS1, as a mitotic regulator that controls the metaphase-to-anaphase transition. We showed that the le...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533204/ https://ncbi.nlm.nih.gov/pubmed/18757745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709227105 |
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