Phosphorylation downregulates the DNA-binding activity of simian virus 40 T antigen.

Proteolytic fragments of simian virus 40 tumor (T) antigen and T antigen that was dephosphorylated with alkaline phosphatase bound between 1.5 to 2 times more origin-containing simian virus 40 DNA than did intact T antigen in DNA saturation experiments. Kinetic experiments showed that these treatmen...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Simmons, D T, Chou, W, Rodgers, K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023678/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.60.3.888-894.1986
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