Phosphorylation downregulates the DNA-binding activity of simian virus 40 T antigen.
Proteolytic fragments of simian virus 40 tumor (T) antigen and T antigen that was dephosphorylated with alkaline phosphatase bound between 1.5 to 2 times more origin-containing simian virus 40 DNA than did intact T antigen in DNA saturation experiments. Kinetic experiments showed that these treatmen...
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| 出版年: | J Virol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1986
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023678/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.60.3.888-894.1986 |
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