Thyroid Hormone Receptor α1 Follows a Cooperative CRM1/Calreticulin-mediated Nuclear Export Pathway

The thyroid hormone receptor α1 (TRα) exhibits a dual role as an activator or repressor of its target genes in response to thyroid hormone (T(3)). Previously, we have shown that TRα, formerly thought to reside solely in the nucleus bound to DNA, actually shuttles rapidly between the nucleus and cyto...

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Main Authors: Grespin, Matthew E., Bonamy, Ghislain M. C., Roggero, Vincent R., Cameron, Nicole G., Adam, Lindsay E., Atchison, Andrew P., Fratto, Victoria M., Allison, Lizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533095/
https://ncbi.nlm.nih.gov/pubmed/18641393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710482200
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