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S-Adenosylhomocysteine Analogues with the Carbon-5' and Sulfur Atoms Replaced by a "Vinyl Unit"

Cross-metathesis of suitably protected 5'-deoxy-5'-methyleneadenosines with racemic and chiral N-Boc protected six-carbon amino acids bearing a terminal double bond in the presence of the Hoveyda-Grubbs catalyst gave adenosylhomocysteine analogues with the C5'–C6' double bond. Br...

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Detalhes bibliográficos
Main Authors: Andrei, Daniela, Wnuk, Stanislaw F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532837/
https://ncbi.nlm.nih.gov/pubmed/17048851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol062026m
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