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Synthesis of the Multisubstituted Halogenated Olefins via Cross-Coupling of Dihaloalkenes with Alkylzinc Bromides

The 1-fluoro-1-haloalkenes undergo Pd-catalyzed Negishi cross-couplings with primary alkylzinc bromides to give multisubstituted fluoroalkenes. The alkylation was trans-selective giving pure Z-fluoroalkenes in most cases. The highest yields were obtained with Pd(2)(dba)(3) and PdCl(2)(dppb) catalyst...

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Sonraí Bibleagrafaíochta
Main Authors: Andrei, Daniela, Wnuk, Stanislaw F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527053/
https://ncbi.nlm.nih.gov/pubmed/16388671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo051980e
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