SIRT3 interacts with the daf-16 homolog FOXO3a in the Mitochondria, as well as increases FOXO3a Dependent Gene expression

Cellular longevity is a complex process relevant to age-related diseases including but not limited to chronic illness such as diabetes and metabolic syndromes. Two gene families have been shown to play a role in the genetic regulation of longevity; the Sirtuin and FOXO families. It is also establish...

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Detalhes bibliográficos
Main Authors: Jacobs, Kristi Muldoon, Pennington, J. Daniel, Bisht, Kheem S., Aykin-Burns, Nukhet, Kim, Hyun-Seok, Mishra, Mark, Sun, Lunching, Nguyen, Phuongmai, Ahn, Bong-Hyun, Leclerc, Jaime, Deng, Chu-Xia, Spitz, Douglas R., Gius, David
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2008
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532794/
https://ncbi.nlm.nih.gov/pubmed/18781224
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