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Direct Asymmetric anti-Mannich-Type Reactions Catalyzed by a Designed Amino Acid
The development of catalysts for Mannich-type reactions that afford anti-products with excellent diastereo- and enantioselectivities under mild conditions and low catalyst loadings (1–5 mol%) is reported. Based on principles gained from the study of (S)-proline-catalyzed Mannich-type reactions that...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2532695/ https://ncbi.nlm.nih.gov/pubmed/16433496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja056984f |
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