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Regioselective Copper-catalyzed Amination of Bromobenzoic Acids Using Aliphatic and Aromatic Amines
[Image: see text] A chemo- and regioselective copper-catalyzed cross-coupling procedure for amination of 2-bromobenzoic acids is described. The method eliminates the need for acid protection and produces N-aryl and N-alkyl anthranilic acid derivatives in up to 99%. N-(1-Pyrene)anthranilic acid has b...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2531286/ https://ncbi.nlm.nih.gov/pubmed/16599627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo060034a |
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