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Regioselective Copper-catalyzed Amination of Bromobenzoic Acids Using Aliphatic and Aromatic Amines

[Image: see text] A chemo- and regioselective copper-catalyzed cross-coupling procedure for amination of 2-bromobenzoic acids is described. The method eliminates the need for acid protection and produces N-aryl and N-alkyl anthranilic acid derivatives in up to 99%. N-(1-Pyrene)anthranilic acid has b...

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Detalhes bibliográficos
Main Authors: Wolf, Christian, Liu, Shuanglong, Mei, Xuefeng, August, Adam T., Casimir, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531286/
https://ncbi.nlm.nih.gov/pubmed/16599627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo060034a
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