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Synthesis and Biological Activity of Phospholipase C-Resistant Analogues of Phosphatidylinositol 4, 5-bisphosphate
The membrane phospholipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2)) is an important regulator in cell physiology. Hydrolysis of PtdIns(4,5)P(2) by phospholipase C (PLC) releases two second messengers, Ins(1,4,5)P(3) and diacylglycerol. To dissect the effects of PtdIns(4,5)P(2) from tho...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2531207/ https://ncbi.nlm.nih.gov/pubmed/16637624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja060621d |
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