Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy

BACKGROUND: Drug resistance can be complex, and several mutations responsible for it can co-exist in a resistant cell. Transcriptional profiling is ideally suited for studying complex resistance genotypes and has the potential to lead to novel discoveries. We generated full genome 70-mer oligonucleo...

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Autori principali: Ubeda, Jean-Michel, Légaré, Danielle, Raymond, Frédéric, Ouameur, Amin Ahmed, Boisvert, Sébastien, Rigault, Philippe, Corbeil, Jacques, Tremblay, Michel J, Olivier, Martin, Papadopoulou, Barbara, Ouellette, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2530873/
https://ncbi.nlm.nih.gov/pubmed/18638379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-7-r115
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