Epidermal Growth Factor Signaling and Mitogenesis in Plcg1 Null Mouse Embryonic Fibroblasts
Gene targeting techniques and early mouse embryos have been used to produce immortalized fibroblasts genetically deficient in phospholipase C (PLC)-γ1, a ubiquitous tyrosine kinase substrate. Plcg1(−/−) embryos die at embryonic day 9; however, cells derived from these embryos proliferate as well as...
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| Publicado no: | Mol Biol Cell |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Cell Biology
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25303/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9529375/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.9.4.749 |
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